Targeting complement C3a receptor resolves mitochondrial hyperfusion and subretinal microglial activation in progranulin-deficient frontotemporal dementia

Tan LX, Oertel FC, Cheng A, Cobigo Y, Keihani A, Bennett DJ, Abdelhak A, Montes SC, Chapman M, Chen RY, Cordano C, Ward ME, Casaletto K, Kramer JH, Rosen HJ, Boxer A, Miller BL, Green AJ, Elahi FM*, Lakkaraju A* (2024) bioRxiv

Vascular Cognitive Impairment

Windon C, Elahi FM, In: Ovbiagele B, Kim AS (eds) (2024) Ischemic Stroke Therapeutics

Plasma proteomics of genetic brain arteriosclerosis and dementia syndrome identifies signatures of fibrosis, angiogenesis, and metabolic alterations

Keller JN, Radabaugh H, Karvelas N, Fitzsimons S, Treiman S, Palafox MF, McDonnell L, Quiroz YT, Lopera FJ, Banerjee D, Wang MM, Arboleda-Velasquez JF, Meschia JF, Ferguson AR, Elahi FM (2024) bioRxiv

Enlarged perivascular spaces are associated with white matter injury, cognition and inflammation in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

Karvelas N, Oh B, Wang E, Cobigo Y, Tsuei T, Fitzsimons S, Younes K, Ehrenberg A, Geschwind MD, Schwartz D, Kramer JH, Ferguson AR, Miller BL, Silbert LC, Rosen HJ, Elahi FM (2024) Brain Communications

Proteomic profiling of intracranial atherosclerotic plaque in the human brain

Hao Q, Wang E, Wang J, Wu Z, Crary JF, Sharma S, Thorn EL, Elahi FM, Zhang B, Peng J (2024) bioRxiv

Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer’s disease: Opportunities for therapy

Kelly L, Brown C, Michalik D, Hawkes CA, Aldea R, Agarwal N, Salib R, Alzetani A, Ethell DW, Counts SE, de Leon M, Fossati S, Koronyo-Hamaoui M, Piazza F, Rich SA, Wolters FJ, Snyder H, Ismail O, Elahi F, Proulx ST, Verma A, Wunderlich H, Haack M, Dodart JC, Mazer N, Carare RO (2023) Alzheimer's & Dementia

Management of inherited CNS small vessel diseases: the CADASIL example: a scientific statement from the American Heart Association

Meschia JF, Worrall BB, Elahi FM, Ross OA, Wang MM, Goldstein ED, Rost NS, Majersik JJ, Gutierrez J; on behalf of the American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and Council on Hypertension (2023) Stroke

PDE5 inhibitor drugs for use in dementia

Hainsworth AH, Arancio O, Elahi FM, Isaacs JD, Cheng F (2023) Alzheimer's & Dementia

Divergent enlarged perivascular spaces volumes in early versus late age-of-onset Alzheimer’s disease

Younes K, Cobbigo Y, Tsuie T, Wang E, Wolf A, Schwartz D, La Joie R, Soleimani-Meigooni DN, Asken B, Mundada NS, Tosun D, Kramer JH, Ferguson A, Mormino E, Miller BL, Silbert L, Rabinovici G, Rosen HJ, Elahi FM (2023) medRxiv

Clinical trials in vascular cognitive impairment following SPRINT-MIND: An international perspective

Elahi FM, Wang M & Meschia J (2023) Stroke

Novel grading system for CADASIL severity: a multicenter cross-sectional study

Elahi FM, Wang M & Meschia J (2023) Stroke

White matter hyperintensities: Complex predictor of complex outcomes

Elahi FM, Wang M & Meschia J (2023) Stroke

Advances in neurodegenerative disease research: Setting the stage for new therapeutics

Elahi FM, Wang M & Meschia J (2023) Stroke

Cerebral small vessel disease (CSVD)-related dementia: more questions than answers

Elahi FM, Wang M & Meschia J (2023) Stroke

Placental growth factor as a sensitive biomarker for vascular cognitive impairment

Hinman JD, Elahi FM, Chong D, Radabaugh H, Ferguson A, Maillard P, Thompson JF, Rosenberg GA, Sagare A, Moghekar A, Lu H, Lee T, Wilcock D, Satizabal CL, Tracy R, Seshadri S, Schwab K, Helmer K, Singh H, Kivisäkk P, Greenberg S, DeCarli C, Kramer J (2023) Alzheimer’s & Dementia

Immune cell counts in cerebrospinal fluid predict cognitive function in aging and neurodegenerative disease

Snyder A, Grant H, Chou A, Lindbergh CA, Kramer JH, Miller BL, Elahi FM (2023) Alzheimer’s & Dementia

Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model

Roseborough AD, Myers SJ, Khazee R, Zhu Y, Zhao L, Iorio E, Elahi FM, Pasternak SH, Whitehead SN (2023) Journal of Neuroinflammation

Lower white matter volume and worse executive functioning reflected in higher levels of plasma GFAP among older adults with and without cognitive impairment

Asken BM, VandeVrede L, Rojas JC, Fonseca C, Staffaroni AM, Elahi FM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Boxer AL, Miller BL, Rosen HJ, Kramer JH, Casaletto KB (2022) Journal of the International Neuropsychological Society

Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology

Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Cosima Oertel F, Arfanakis K, Staffaroni AM, Kramer JH, Geshwind M, Miller BL, Elahi FM, Green AJ (2022) Alzheimer’s & Dementia

Right temporal degeneration and socioemotional semantics: Semantic behavioural variant frontotemporal dementia

Younes K, Borghesani V, Montembeault M, Spina S, Mandelli ML, Welch AE, Weis E, Callahan P, Elahi FM, Hua AY, Perry DC, Karydas A, Geschwind D, Huang E, Grinberg LT, Kramer JH, Boxer AL, Rabinovici GD, Rosen HJ, Seeley WW, Miller ZA, Miller BL, Sturm VE, Rankin KP, Luisa Gorno-Tempini M (2022) Brain